2bel: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2bel.gif|left|200px]]<br /> | [[Image:2bel.gif|left|200px]]<br /><applet load="2bel" size="450" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="2bel" size="450" color="white" frame="true" align="right" spinBox="true" | |||
caption="2bel, resolution 2.11Å" /> | caption="2bel, resolution 2.11Å" /> | ||
'''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE'''<br /> | '''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE'''<br /> | ||
| Line 8: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
2BEL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CL, NAP and CBO as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] | 2BEL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CL, NAP and CBO as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] Known structural/functional Site: <scene name='pdbsite=AC1:Cl Binding Site For Chain C'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BEL OCA]. | ||
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 38: | Line 37: | ||
[[Category: steroid metabolism]] | [[Category: steroid metabolism]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 18:44:04 2007'' | ||
Revision as of 16:34, 18 December 2007
|
STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE
Disease
Known diseases associated with this structure: Cortisone reductase deficiency OMIM:[600713]
About this Structure
2BEL is a Single protein structure of sequence from Homo sapiens with CL, NAP and CBO as ligands. Active as 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146 Known structural/functional Site: AC1. Full crystallographic information is available from OCA.
Page seeded by OCA on Tue Dec 18 18:44:04 2007
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- 11-beta-hydroxysteroid dehydrogenase
- Homo sapiens
- Single protein
- Abrahmsen, L.
- Arrowsmith, C.
- Bray, J.
- Debreczeni, J.E.
- Delft, F.Von.
- Edwards, A.
- Elleby, B.
- Kavanagh, K.
- Oppermann, U.
- Sharma, S.
- Sundstrom, M.
- Svensson, S.
- Wu, X.
- CBO
- CL
- NAP
- Drug target
- Glucocorticoid activation
- Hormone metabolism
- Inhibitor
- Microsome
- Nadp
- Oxidoreductase
- Short-chain dehydrogenase/reductase
- Steroid metabolism
