3m2w: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3m2w.jpg|left|200px]]


The entry 3m2w is ON HOLD
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{{STRUCTURE_3m2w|  PDB=3m2w |  SCENE=  }}


Authors: Kroemer, M., Revesz, L., Be, C., Izaac, A., Huppertz, C., Schlapbach, A., Scheufler, C.
===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor===


Description: Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:38:06 2010''
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{{ABSTRACT_PUBMED_20591669}}
 
==About this Structure==
3M2W is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA].
 
==Reference==
<ref group="xtra">PMID:20591669</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Be, C.]]
[[Category: Huppertz, C.]]
[[Category: Izaac, A.]]
[[Category: Kroemer, M.]]
[[Category: Revesz, L.]]
[[Category: Scheufler, C.]]
[[Category: Schlapbach, A.]]
[[Category: Atp-binding]]
[[Category: Atp-site kinase inhibitor]]
[[Category: Kinase]]
[[Category: Novartis compound nvp-bxs169]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Small molecule inhibitor]]
[[Category: Spiroazetidine-tetracycle]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:37:21 2010''

Revision as of 08:30, 28 July 2010

File:3m2w.jpg

Template:STRUCTURE 3m2w

Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor

Template:ABSTRACT PUBMED 20591669

About this Structure

3M2W is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Revesz L, Schlapbach A, Aichholz R, Dawson J, Feifel R, Hawtin S, Littlewood-Evans A, Koch G, Kroemer M, Mobitz H, Scheufler C, Velcicky J, Huppertz C. In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4719-23. Epub 2010 Apr 11. PMID:20591669 doi:10.1016/j.bmcl.2010.04.023

Page seeded by OCA on Wed Jul 28 12:37:21 2010

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