Reverse transcriptase: Difference between revisions

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{{STRUCTURE_1hmv|  PDB=1hmv  | SIZE=300| SCENE=Reverse_transcriptase/Cv/1 |right|CAPTION=HIV-1 Reverse transcriptase, [[1hmv]] }}
{{STRUCTURE_1hmv|  PDB=1hmv  | SIZE=300| SCENE=Reverse_transcriptase/Cv/1 |right|CAPTION=HIV-1 Reverse transcriptase, [[1hmv]] }}


 
[[Reverse transcriptase]] (RT) or RNA-dependent DNA polymerase transcribes single-stranded RNA into double-stranded DNA.  HIV-1 RT is from the human immunodeficiency virus and is a heterodimer of P66 and P51. The images at the left and at the right correspond to one representative RT structure, ''i.e.'' crystal structure of HIV-1 Reverse transcriptase ([[1hmv]]). P15 is its RNAse H domain.  NNRTI are the non-nucleoside inhibitors of HIV-1 RT.  M-MLV is RT from the leukemia virus.


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