User:Wayne Decatur/kink-turn motif: Difference between revisions
From Proteopedia
Jump to navigationJump to search
mNo edit summary |
mNo edit summary |
||
| Line 10: | Line 10: | ||
'''The kink-turn motif'''<br> | '''The kink-turn motif'''<br> | ||
A common RNA structural motif that consists of helix–internal loop–helix motif . | A common RNA structural motif that consists of helix–internal loop–helix motif that introduces a very tight kink into the helical axis. | ||
| Line 16: | Line 16: | ||
Originally identified in the course of analyzing the [[Large Ribosomal Subunit of Haloarcula|large ribosomal subunit]]<ref name="kleinref">PMID: 11483524</ref>, this RNA structural motif was also identified in other RNAs. Particular instances have been called the GA motif <ref>PMID: 11497434</ref> | Originally identified in the course of analyzing the [[Large Ribosomal Subunit of Haloarcula|large ribosomal subunit]]<ref name="kleinref">PMID: 11483524</ref>, this RNA structural motif was also identified in other RNAs. Particular instances have been called the GA motif <ref>PMID: 11497434</ref> | ||
The kink-turn motif includes the [[A-minor motif]]. | The kink-turn motif includes the [[A-minor motif]]. | ||
Many kink-turns bind proteins; however, | Many kink-turns bind proteins; however, that trait is not universal. They can mediate RNA tertiary structure interactions as well. | ||
An excellent introduction can be found [http://www.dundee.ac.uk/biocentre/nasg/kturn/index.php here as part of a structural database for k-turn motifs in RNA by the Lilley group]<ref name="lilleydatabase">PMID: 20562215</ref>. | An excellent introduction can be found [http://www.dundee.ac.uk/biocentre/nasg/kturn/index.php here as part of a structural database for k-turn motifs in RNA by the Lilley group]<ref name="lilleydatabase">PMID: 20562215</ref>. | ||
