User:Wayne Decatur/kink-turn motif: Difference between revisions
From Proteopedia
Jump to navigationJump to search
| Line 23: | Line 23: | ||
{{Kinkturnapplet}} | {{Kinkturnapplet}} | ||
* [[Large Ribosomal Subunit of Haloarcula|The Large Ribosomal Subunit]] contains 9 identified kink-turns<ref name="kleinref" /><ref name="lilleydatabase" />: <scene name='User:Wayne_Decatur/kink-turn_motif/Kt7withproteins/9'>Kt-7</scene> (Kt-7 <scene name='User:Wayne_Decatur/kink-turn_motif/Kt7withproteins/10'>with bound proteins</scene>),Kt-58 of [[3cc2]]; Kt-78 as observed in [[2wh2]] (While present based on sequence comparison, Kt-78 is in a portion of the large subunit not visible in the crystal structure of [[3cc2]].) | * [[Large Ribosomal Subunit of Haloarcula|The Large Ribosomal Subunit]] contains 9 identified kink-turns<ref name="kleinref" /><ref name="lilleydatabase" />: <scene name='User:Wayne_Decatur/kink-turn_motif/Kt7withproteins/9'>Kt-7</scene> (Kt-7 <scene name='User:Wayne_Decatur/kink-turn_motif/Kt7withproteins/10'>with bound proteins</scene>),Kt-58 of [[3cc2]]; Kt-78 as observed in [[2wh2]] (While present based on sequence comparison, Kt-78 is in a portion of the large subunit not visible in the crystal structure of [[3cc2]].) | ||
:* <scene name='User:Wayne_Decatur/kink-turn_motif/3cc2withkiturns/7'>The location of the eight | :* <scene name='User:Wayne_Decatur/kink-turn_motif/3cc2withkiturns/7'>The location of the eight kink-turns</scene> observed in the solved structure of [[Large Ribosomal Subunit of Haloarcula|the Haloarcula large ribosomal subunit]] shows they are on the surface of the subunit. (A ninth kink-turn, Kt-78, is not resolved in the ''Haloarcula marismortui'' structure but is also on the surface.) | ||
:* See all of the 23S rRNA kink-turns and others on this page in greater detail following the appropriate links on [http://www.dundee.ac.uk/biocentre/nasg/kturn/kturns_known.php this page at a structural database for k-turn motifs in RNA by the Lilley group]<ref name="lilleydatabase" />. | :* See all of the 23S rRNA kink-turns and others on this page in greater detail following the appropriate links on [http://www.dundee.ac.uk/biocentre/nasg/kturn/kturns_known.php this page at a structural database for k-turn motifs in RNA by the Lilley group]<ref name="lilleydatabase" />. | ||
* The human spliceosomal and small nucleolar RNA-binding 15.5kD protein bound to the kink-turn of a U4 spliceosomal RNA fragment ([[1e7k]])<ref name="u4xstal">PMID: 11163207</ref>. The fact both the box C/D small nucleolar RNAs and the spliceosomal U4 RNA share this motif, and in fact bind the same protein, was observed<ref>PMID: 11081632</ref><ref name="u4xstal" /> even before the kink-turn was shown to be a widespread motif. | * The human spliceosomal and small nucleolar RNA-binding 15.5kD protein bound to the kink-turn of a U4 spliceosomal RNA fragment ([[1e7k]])<ref name="u4xstal">PMID: 11163207</ref>. The fact both the box C/D small nucleolar RNAs and the spliceosomal U4 RNA share this motif, and in fact bind the same protein, was observed<ref>PMID: 11081632</ref><ref name="u4xstal" /> even before the kink-turn was shown to be a widespread motif. | ||
