2k4l: Difference between revisions

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[[Image:2k4l.jpg|left|200px]]
[[Image:2k4l.png|left|200px]]


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==About this Structure==
==About this Structure==
2K4L is a [[Single protein]] structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4L OCA].  
2K4L is a 2 chains structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4L OCA].  


==Reference==
==Reference==
Solution Structure of a 2:1 C2-(2-Naphthyl) Pyrrolo[2,1-c][1,4]benzodiazepine DNA Adduct: Molecular Basis for Unexpectedly High DNA Helix Stabilization., Antonow D, Barata T, Jenkins TC, Parkinson GN, Howard PW, Thurston DE, Zloh M, Biochemistry. 2008 Oct 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18925745 18925745]
<ref group="xtra">PMID:18925745</ref><ref group="xtra">PMID:17397227</ref><references group="xtra"/>
 
Parallel synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) library., Antonow D, Cooper N, Howard PW, Thurston DE, J Comb Chem. 2007 May-Jun;9(3):437-45. Epub 2007 Mar 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17397227 17397227]
[[Category: Single protein]]
[[Category: Antonow, D.]]
[[Category: Antonow, D.]]
[[Category: Barata, T.]]
[[Category: Barata, T.]]
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[[Category: Thurston, D E.]]
[[Category: Thurston, D E.]]
[[Category: Zloh, M.]]
[[Category: Zloh, M.]]
[[Category: Dna]]
[[Category: Dna adduct]]
[[Category: Dna adduct]]
[[Category: Pbd]]
[[Category: Pbd]]


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Revision as of 19:55, 11 August 2010

File:2k4l.png

Template:STRUCTURE 2k4l

Solution structure of a 2:1C2-(2-naphthyl)pyrrolo[2,1-c][1,4]benzodiazepine (PBD) DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.

Template:ABSTRACT PUBMED 18925745

About this Structure

2K4L is a 2 chains structure. Full experimental information is available from OCA.

Reference

  1. Antonow D, Barata T, Jenkins TC, Parkinson GN, Howard PW, Thurston DE, Zloh M. Solution Structure of a 2:1 C2-(2-Naphthyl) Pyrrolo[2,1-c][1,4]benzodiazepine DNA Adduct: Molecular Basis for Unexpectedly High DNA Helix Stabilization. Biochemistry. 2008 Oct 17. PMID:18925745 doi:10.1021/bi801225q
  2. Antonow D, Cooper N, Howard PW, Thurston DE. Parallel synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) library. J Comb Chem. 2007 May-Jun;9(3):437-45. Epub 2007 Mar 31. PMID:17397227 doi:10.1021/cc0601332

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