3mxw: Difference between revisions

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{{Seed}}
{{Seed}}
[[Image:3mxw.jpg|left|200px]]
[[Image:3mxw.png|left|200px]]


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==Disease==
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Known disease associated with this structure: Coloboma, ocular OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]], Holoprosencephaly-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]], Microphthalmia, isolated, with coloboma 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]], Solitary median maxillary central incisor OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600725 600725]]
The line below this paragraph, {{ABSTRACT_PUBMED_20504762}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 20504762 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20504762}}


==About this Structure==
==About this Structure==
3MXW is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXW OCA].  
3MXW is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXW OCA].  
==Reference==
<ref group="xtra">PMID:20504762</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hymowitz, S G.]]
[[Category: Hymowitz, S G.]]
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[[Category: Zinc hydrolase]]
[[Category: Zinc hydrolase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:35:47 2010''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:12:57 2010''

Revision as of 20:05, 11 August 2010

File:3mxw.png

Template:STRUCTURE 3mxw

Crystal structure Sonic hedgehog bound to the 5E1 fab fragment

Template:ABSTRACT PUBMED 20504762

About this Structure

3MXW is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Maun HR, Wen X, Lingel A, de Sauvage FJ, Lazarus RA, Scales SJ, Hymowitz SG. Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site. J Biol Chem. 2010 Aug 20;285(34):26570-80. Epub 2010 May 26. PMID:20504762 doi:10.1074/jbc.M110.112284

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