2uwl: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2uwl.gif|left|200px]]<br /> | [[Image:2uwl.gif|left|200px]]<br /><applet load="2uwl" size="450" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="2uwl" size="450" color="white" frame="true" align="right" spinBox="true" | |||
caption="2uwl, resolution 1.90Å" /> | caption="2uwl, resolution 1.90Å" /> | ||
'''SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA'''<br /> | '''SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA'''<br /> | ||
| Line 8: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
2UWL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with 895 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] | 2UWL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with 895 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] Known structural/functional Site: <scene name='pdbsite=AC1:895 Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2UWL OCA]. | ||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 42: | Line 41: | ||
[[Category: zymogen]] | [[Category: zymogen]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 20:19:02 2007'' | ||
Revision as of 18:09, 18 December 2007
|
SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA
Disease
Known disease associated with this structure: Factor X deficiency OMIM:[227600]
About this Structure
2UWL is a Single protein structure of sequence from Homo sapiens with 895 as ligand. Active as Coagulation factor Xa, with EC number 3.4.21.6 Known structural/functional Site: AC1. Full crystallographic information is available from OCA.
Page seeded by OCA on Tue Dec 18 20:19:02 2007
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Single protein
- Brown, D.
- Burns-Kurtis, C.L.
- Chan, C.
- Convery, M.A.
- Hubbard, J.A.
- Kelly, H.A.
- Pateman, A.J.
- Patikis, A.
- Senger, S.
- Shah, G.P.
- Toomey, J.R.
- Watson, N.S.
- Young, R.J.
- Zhou, P.
- 895
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Complex
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Polymorphism
- Protease
- Serine protease
- Target hopping
- Zymogen