3msl: Difference between revisions
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===Fragment Based Discovery and Optimisation of BACE-1 Inhibitors=== | ===Fragment Based Discovery and Optimisation of BACE-1 Inhibitors=== | ||
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==About this Structure== | ==About this Structure== | ||
3MSL is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSL OCA]. | 3MSL is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSL OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:20656487</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:21:26 2010'' | ||
Revision as of 05:13, 1 September 2010
Fragment Based Discovery and Optimisation of BACE-1 Inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3MSL is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Page seeded by OCA on Wed Sep 1 09:21:26 2010
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Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Barker, J.
- Madden, J.
- Smith, M.
- Alzheimer's disease
- Amyloid precursor protein secretase
- Aspartic endopeptidase
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Fluorescence polarisation
- Fragment-based drug design
- Glycoprotein
- Hydrolase
- Protease
- Transmembrane
- Zymogen
