3msj: Difference between revisions
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===Structure of bace (beta secretase) in complex with inhibitor=== | ===Structure of bace (beta secretase) in complex with inhibitor=== | ||
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{{ABSTRACT_PUBMED_20656487}} | |||
==About this Structure== | ==About this Structure== | ||
3MSJ is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSJ OCA]. | 3MSJ is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSJ OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:20656487</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:21:31 2010'' | ||
Revision as of 05:13, 1 September 2010
Structure of bace (beta secretase) in complex with inhibitor
Template:ABSTRACT PUBMED 20656487
About this Structure
3MSJ is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Page seeded by OCA on Wed Sep 1 09:21:31 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Barker, J.
- Godemann, R.
- Kramer, J.
- Madden, J.
- Smith, M A.
- Alzheimer's disease
- Amyloid precursor protein secretase
- Aspartic endopeptidase
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Fluorescence polarisation
- Fragment-based drug design
- Glycoprotein
- Hydrolase
- Protease
- Transmembrane
- Zymogen
