Agrin: Difference between revisions

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New page: left|200px|thumb|Crystal Structure of chicken Agrin, [[3i70]] {{STRUCTURE_3i70| PDB=3i70 | SIZE=300| SCENE= |right|CAPTION=chicken Agrin, 3i70 }} Agrin (Agr) ...
 
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[[Image:3i70.png|left|200px|thumb|Crystal Structure of chicken Agrin, [[3i70]]]]
[[Image:3i70.jpg|left|200px|thumb|Crystal Structure of chicken Agrin, [[3i70]]]]
{{STRUCTURE_3i70|  PDB=3i70  | SIZE=300| SCENE= |right|CAPTION=chicken Agrin, [[3i70]] }}
{{STRUCTURE_3i70|  PDB=3i70  | SIZE=300| SCENE=Agrin/Cv/1 |right|CAPTION=chicken Agrin, [[3i70]] }}


[[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction.  It is involved in the aggregation of acetylcholine receptors.  Its N-terminal domain NtA binds laminin. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]).
[[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction.  It is involved in the aggregation of acetylcholine receptors.  Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]).


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Revision as of 11:53, 16 September 2010

File:3i70.jpg
Crystal Structure of chicken Agrin, 3i70

Template:STRUCTURE 3i70

Agrin (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, i.e. the crystal structure of chicken Agrin (3i70).

3D Structures of Agrin

3i70, 1pxu – cNtA – chicken
1pz7, 1pz8, 1pz9 – cAgr
1q56 – cAgr-G3+Ca – NMR
1jb3, 1jc7 – cAgr LMB

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Alexander Berchansky, Michal Harel, Joel L. Sussman