Thermolysin: Difference between revisions
No edit summary |
No edit summary |
||
| Line 9: | Line 9: | ||
== Thermolysin == | === Thermolysin === | ||
Revision as of 12:34, 13 October 2010
Thermolysin (TML) is a thermostable metalloproteinase enzyme from Bacillus thermoproteolyticus. It catalyzes the hydrolysis of peptide bonds containing hydrophobic residues. The images at the left and at the right correspond to one representative Thermolysin (3dnz).
3D Structures of Thermolysin
Thermolysin
2whz, 3fvp, 3dnz, 3do0, 3do1, 3do2, 2g4z, 2a7g, 1gxw, 1kei, 1l3f, 1tlx, 2tlx, 8tln – TML
1trl - TML residues 255-316 – NMR
3fxs, 3fbo, 3eim, 1lna, 1lnb, 1lnc, 1lnd, 1lne, 1lnf - TML residues 233-548+metal ion replacing Ca
TML+transition state analog
1tlp, 1tmn, 2tmn, 4tmn, 5tmn – TML+transition state analog
TML+ dipeptide
2wi0, 3tmn – TML+ dipeptide
3fgd - TML residues 233-548+dipeptide
TML+inhibitor
1fjo, 1fj3, 1fjq, 1fjt, 1fju, 1fjv, 1fjw, 4tli, 5tli, 6tli, 7tli, 8tli, 1tli, 2tli, 3tli – TML soaked in organic solvents
3fv4, 3fxp, 3flf, 3fb0, 3fcq, 3f28, 3f2p – TML residues 233-548+inhibitor
3fwd, 3for, 1y3g, 1zdp, 1z9g, 1pes, 1pe7, 1pe8, 1os0, 1kto, 1ks7, 1kro, 1kr6, 1kkk, 1kjo, 1kjp, 1qf0, 1qf1, 1qf2, 1hyt, 1thl, 6tmn, 7tln, 4tln, 5tln – TML+inhibitor
