3mvm: Difference between revisions
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[[Image:3mvm. | [[Image:3mvm.png|left|200px]] | ||
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[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:27:21 2010'' | ||
Revision as of 08:16, 27 October 2010
P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V
Template:ABSTRACT PUBMED 20804198
About this Structure
3MVM is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu C, Lin J, Wrobleski ST, Lin S, Hynes J, Wu H, Dyckman AJ, Li T, Wityak J, Gillooly KM, Pitt S, Shen DR, Zhang RF, McIntyre KW, Salter-Cid L, Shuster DJ, Zhang H, Marathe PH, Doweyko AM, Sack JS, Kiefer SE, Kish KF, Newitt JA, McKinnon M, Dodd JH, Barrish JC, Schieven GL, Leftheris K. Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[ 1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. J Med Chem. 2010 Sep 23;53(18):6629-39. PMID:20804198 doi:10.1021/jm100540x
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