3n2v: Difference between revisions
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===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide=== | |||
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{{ABSTRACT_PUBMED_20965620}} | |||
==About this Structure== | |||
3N2V is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2V OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20965620</ref><ref group="xtra">PMID:17269766</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Macrophage elastase]] | |||
[[Category: Calderone, V.]] | |||
[[Category: Elastase]] | |||
[[Category: Extracellular matrix]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Hydrolase]] | |||
[[Category: Matrix metalloproteinase]] | |||
[[Category: Metal-inding]] | |||
[[Category: Metallo elastase]] | |||
[[Category: Metalloprotease]] | |||
[[Category: Mmp12]] | |||
[[Category: Protease]] | |||
[[Category: Secreted]] | |||
[[Category: Zymogen]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:49:26 2010'' | |||
Revision as of 03:38, 10 November 2010
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide
Template:ABSTRACT PUBMED 20965620
About this Structure
3N2V is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Attolino E, Calderone V, Dragoni E, Fragai M, Richichi B, Luchinat C, Nativi C. Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs). Eur J Med Chem. 2010 Oct 19. PMID:20965620 doi:10.1016/j.ejmech.2010.09.057
- Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z
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