AZT-resistant HIV-1 reverse transcriptase: Difference between revisions
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==AZT Resistance== | ==AZT Resistance== | ||
There are two basic types of resistance mechanisms currently known for HIV-1: | |||
1. exclusion- discrimination between AZTTP and dTTP at the time that AZTTP is incorporated | |||
2. excision- removal of AZTTP from the viral DNA after it has been incorporated into the host genome | |||
==References== | ==References== | ||