AZT-resistant HIV-1 reverse transcriptase: Difference between revisions
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Two distinct domains, polymerase and RNase H form the p66 subunit. The polymerase domain consists of four subdomains: fingers (residues 1-85 and 118-155), palm (residues 86-117 and 156-236), thumb (residues 237-318), and connection (residues 319-426). The p51 subunit folds into the same subdomains, but the positions of the subdomains relative to each other are different. | Two distinct domains, polymerase and RNase H form the p66 subunit. The polymerase domain consists of four subdomains: fingers (residues 1-85 and 118-155), palm (residues 86-117 and 156-236), thumb (residues 237-318), and connection (residues 319-426). The p51 subunit folds into the same subdomains, but the positions of the subdomains relative to each other are different. | ||
[[Image:RT finger.png]] | [[Image:RT finger.png]] [[Image:RT palm.png]] | ||
'''Fingers Subdomain''' | '''Fingers Subdomain''' ''' Palm Subdomain''' | ||
