Luciferase: Difference between revisions
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==See Also== | ==See Also== | ||
<applet load='2d1s' size='450' frame='true' align='right' scene='Luciferase/2d1s/1' caption='Luciferase ([[Luciola cruciata luciferase|2d1s]]) {{Link Toggle FancyCartoonHighQualityView}}.' /> | <applet load='2d1s' size='450' frame='true' align='right' scene='Luciferase/2d1s/1' caption='Luciferase ([[Luciola cruciata luciferase|2d1s]]) {{Link Toggle FancyCartoonHighQualityView}}.' /> | ||
*[[Japanese firefly Luciferase complexed with Oxyluciferin & AMP]] | |||
*[[Luciola cruciata luciferase]] | *[[Luciola cruciata luciferase]] | ||
*[[3ies]],[[3iep]] and [[3ier]] Firefly luciferase (FLuc) bound to its natural substrate ATP and the inhibitor PTC124<ref>PMID: 20194791</ref> | *[[3ies]],[[3iep]] and [[3ier]] Firefly luciferase (FLuc) bound to its natural substrate ATP and the inhibitor PTC124<ref>PMID: 20194791</ref> | ||
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*[[Green Fluorescent Protein]] | *[[Green Fluorescent Protein]] | ||
* For additional information, see: [[Colored & Bioluminescent Proteins]] | * For additional information, see: [[Colored & Bioluminescent Proteins]] | ||
==References== | ==References== | ||
Revision as of 13:00, 24 November 2010
Introduction
Several organisms are bioluminescent, meaning that they produce light. Luciferase is one of the enzymes that catalyzes light emitting reactions in organisms.
See Also
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- Japanese firefly Luciferase complexed with Oxyluciferin & AMP
- Luciola cruciata luciferase
- 3ies,3iep and 3ier Firefly luciferase (FLuc) bound to its natural substrate ATP and the inhibitor PTC124[1]
- 1ba3 firefly luciferase enzyme from Photinus pyralis
- 2psd, 2pse, 2psf, 2psh, 2psj, and 2rh7 the luciferase from Renilla reniformis (RLuc)
- 1bsl 1.95Å heterodimer of bacterial luciferase from Vibrio harveyi
- 1brl 2.4Å heterodimer of bacterial luciferase from Vibrio harveyi
- 1xkj homodimer of bacterial luciferase from Vibrio harveyi
- 2d1q, 2d1r and 2d1s thermostable Japanese Firefly (Luciola cruciata) Luciferase complexed with High-energy intermediate analog
- 2d1t thermostable Japanese Firefly Luciferase red-color emission S286N mutant
- 1lci firefly luciferase enzyme from Photinus pyralis
- Dinoflagellate luciferase
- 1luc The 1.5Å resolution crystal structure of bacterial luciferase from Vibrio harveyi
- 3fgc Bacterial luciferase from Vibrio harveyi[2]
- 1vpr luciferase of Lingulodinium polyedrum, a marine bioluminescent dinoflagellate
- Green Fluorescent Protein
- For additional information, see: Colored & Bioluminescent Proteins
References
- ↑ Auld DS, Lovell S, Thorne N, Lea WA, Maloney DJ, Shen M, Rai G, Battaile KP, Thomas CJ, Simeonov A, Hanzlik RP, Inglese J. Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4878-83. Epub 2010 Mar 1. PMID:20194791
- ↑ Campbell ZT, Weichsel A, Montfort WR, Baldwin TO. Crystal Structure of the Bacterial Luciferase:Flavin Complex Provides Insight into the Function of the subunit. Biochemistry. 2009 May 12. PMID:19435287 doi:https://dx.doi.org/10.1021/bi900003t
Additional Literature
- Marques SM, Esteves da Silva JC. Firefly bioluminescence: a mechanistic approach of luciferase catalyzed reactions. IUBMB Life. 2009 Jan;61(1):6-17. PMID:18949818 doi:10.1002/iub.134
- Inouye S. Firefly luciferase: an adenylate-forming enzyme for multicatalytic functions. Cell Mol Life Sci. 2010 Feb;67(3):387-404. Epub 2009 Oct 27. PMID:19859663 doi:10.1007/s00018-009-0170-8
External Resources
- Yahoo news coverage of luciferase studies funded research for military applications
- Luciferase at Wikipedia
- Luciferase: June 2006 Molecule of the Month as part of the series of tutorials that are at the RCSB Protein Data Bank and written by David S. Goodsell
Proteopedia Page Contributors and Editors (what is this?)
Wayne Decatur, Alexander Berchansky, David Canner, Loïc Gazquez, Charlene Planchenault, Michal Harel
