Captopril: Difference between revisions
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{| class="wikitable" border="1" width="50%" style="text-align:center" | {| class="wikitable" border="1" width="50%" style="text-align:center" | ||
|- | |- | ||
! colspan="8" align="center"| ACE-Inhibitor [[Pharmaceutical_Drugs#Pharmacokinetics_Translated|Pharmacokinetics]] Comparison at Equivalent Dosages <ref>PMID: 7867683</ref> <ref>DOI: 10.1111/j.1365-2710.2005.00646.x</ref> <ref>PMID: 15985045</ref> | ! colspan="8" align="center"| ACE-Inhibitor [[Pharmaceutical_Drugs#Pharmacokinetics_Translated|Pharmacokinetics]] Comparison at Equivalent Dosages <ref>PMID: 7867683</ref> <ref>DOI: 10.1111/j.1365-2710.2005.00646.x</ref> <ref>PMID: 15985045</ref><ref>PMID: 16075412</ref> <ref>PMID:7527101</ref> <ref>ISBN:0471752158</ref> | ||
|- | |- | ||
! Parameter | ! Parameter | ||
| Line 30: | Line 30: | ||
! .67 | ! .67 | ||
! 1.06 | ! 1.06 | ||
! | ! .5 | ||
! | ! .75 | ||
! | ! .72 | ||
|- | |- | ||
! [[Pharmaceutical_Drugs#Cmax|C<sub>max</sub>]] (ng/ml) | ! [[Pharmaceutical_Drugs#Cmax|C<sub>max</sub>]] (ng/ml) | ||
| Line 39: | Line 39: | ||
! 16.4 | ! 16.4 | ||
! 314 | ! 314 | ||
! | ! 149 | ||
! | ! 105 | ||
! | ! 1.68 | ||
|- | |- | ||
! [[Pharmaceutical_Drugs#Bioavailability_.28F.29|Bioavailability]] (%) | ! [[Pharmaceutical_Drugs#Bioavailability_.28F.29|Bioavailability]] (%) | ||
| Line 49: | Line 49: | ||
! | ! | ||
! | ! | ||
! | !75 | ||
! | ! | ||
|- | |- | ||
| Line 66: | Line 66: | ||
! 1.93 | ! 1.93 | ||
! 1.6 | ! 1.6 | ||
! | ! 10 | ||
! | ! .9 | ||
! | ! .68 | ||
|- | |- | ||
! [[Pharmaceutical_Drugs#Area_Under_the_Curve_.28AUC.29|AUC]] (ng/ml/hr) | ! [[Pharmaceutical_Drugs#Area_Under_the_Curve_.28AUC.29|AUC]] (ng/ml/hr) | ||
| Line 75: | Line 75: | ||
! 21.9 | ! 21.9 | ||
! 450 | ! 450 | ||
! | ! 140 | ||
! | ! 182 | ||
! | ! 1.86 | ||
|- | |- | ||
! [[Pharmaceutical_Drugs#Inhibitory_Concentration_.28IC50.29|IC<sub>50</sub>]] (nM) | ! [[Pharmaceutical_Drugs#Inhibitory_Concentration_.28IC50.29|IC<sub>50</sub>]] (nM) | ||
! 1.1 | ! 1.1 | ||
! 5.5 | ! 5.5 | ||
! | ! 5.0 | ||
! 5.4 | ! 5.4 | ||
! | ! 1.7 | ||
! | ! 2.4 | ||
! | ! 2.5 | ||
|- | |- | ||
! | ! Dosage (mg) | ||
! 10 | ! 10 | ||
! 20 | ! 20 | ||
| Line 94: | Line 94: | ||
! | ! | ||
! | ! | ||
! | ! | ||
! | ! 2 | ||
|- | |- | ||
! Metabolism | ! Metabolism | ||
| Line 109: | Line 109: | ||
==References== | ==References== | ||
<references/> | <references/> | ||
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__NOTOC__ | |||
