Beta secretase: Difference between revisions
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<applet load="1w51" size="340" color="white" frame="true" align="right" caption="β-Secretase" scene="Beta_secretase/Default/6" /> | <applet load="1w51" size="340" color="white" frame="true" align="right" caption="β-Secretase" scene="Beta_secretase/Default/6" /> | ||
'''β-Secretase''', also known as '''BACE''' ('''β'''-site of '''A'''myloid precursor protein '''C'''leaving '''E'''nzyme) and '''Memapsin 2''' is an aspartyl protease. | '''β-Secretase''', also known as '''BACE''' ('''β'''-site of '''A'''myloid precursor protein '''C'''leaving '''E'''nzyme) and '''Memapsin 2''' is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention. | ||
==Beta Secretase== | ==Beta Secretase== | ||
Revision as of 07:05, 29 November 2010
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β-Secretase, also known as BACE (β-site of Amyloid precursor protein Cleaving Enzyme) and Memapsin 2 is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention.
Beta Secretase
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Alexander Berchansky, Daniel Santos, Michal Harel, Jaime Prilusky, David Canner, Joel L. Sussman