Donepezil: Difference between revisions

! [[Rivastigmine]]

! [[Galantamine]]

|-

! [[Pharmaceutical_Drugs#Tmax|T_max]] (hr)  

! .3

! 1.2

|-

! [[Pharmaceutical_Drugs#Cmax|C_max]] (ng/ml)  

! 29.3

! 42.6

|-

! [[Pharmaceutical_Drugs#Bioavailability_.28F.29|Bioavailability]] (%)

! 36

! 100

|-

! [[Pharmaceutical_Drugs#Protein_Binding|Protein Binding]] (%)

! 40

! 10

|-

! [[Pharmaceutical_Drugs#Half_Life_.28T1.2F2.29|T_1/2]] (hr)

! 5

! 7.3

|-

! [[Pharmaceutical_Drugs#Area_Under_the_Curve_.28AUC.29|AUC]] (ng/ml/hr)

! 191

! 427

|-

! [[Pharmaceutical_Drugs#Inhibitory_Concentration_.28IC50.29|IC₅₀]] (nM)

|-

! Dosage (mg)

! 6

! 8

|-

! Metabolism

! Hepatic (CYP2D6 & CYP3A4)

|}