Indinavir: Difference between revisions

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{| class="wikitable" border="1" width="52%" style="text-align:center"
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!  colspan="12" align="center"| HIV Protease Inhibitor [[Pharmaceutical_Drugs#Pharmacokinetics_Translated|Pharmacokinetics]]<ref>PMID:20400409</ref><ref>Ferry et al, United States Patent US6147095, Pharmacia & Upjohn Company.</ref>
!  colspan="12" align="center"| HIV Protease Inhibitor [[Pharmaceutical_Drugs#Pharmacokinetics_Translated|Pharmacokinetics]]<ref>PMID:20400409</ref><ref>Ferry et al, United States Patent US6147095, Pharmacia & Upjohn Company.</ref><ref>L. Veronese et al. Single-Dose Pharmacokinetics of Amprenavir, a Human Immunodeficiency Virus Type 1 Protease Inhibitor, in Subjects with Normal or Impaired Hepatic  Function. Antimicrob Agents Chemother. 2000 April; 44(4): 821–826.</ref><ref>doi: 10.1128/AAC.48.7.2388-2393.2004.</ref>
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! Parameter
! Parameter
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! 14600
! 14600
! Indinavir
! Indinavir
! Saquinavir
! 1540
! 4901
! 4901
! Fosamprenavir
! Fosamprenavir
Line 84: Line 84:
! 4.2
! 4.2
! 1.8
! 1.8
! 7-12
! 4.5
! 5.56
! 5.56
! Fosamprenavir
! Fosamprenavir
Line 97: Line 97:
! 46500
! 46500
! Indinavir
! Indinavir
! Saquinavir
! 16200
! 11999
! 11999
! Fosamprenavir
! Fosamprenavir