M2 Proton Channel: Difference between revisions

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== Selectivity ==
== Selectivity ==
Because the N-terminus is very constricted near Val27, the M2 channel is highly selective for protons.<ref name="Stouffer" /> The restricted N-terminus only allows protons to penetrate into the aqueous pore through hydrogen-bonded chains of water.<ref name="Stouffer" /> Therefore, it would be extremely difficult for hydrated sodium or potassium to penetrate the restricted areas of the M2 channel.<ref name="Stouffer" />
Because the N-terminus is very constricted near Val27, the M2 channel is highly selective for protons. The restricted N-terminus only allows protons to penetrate into the aqueous pore through hydrogen-bonded chains of water. Therefore, it would be extremely difficult for hydrated sodium or potassium to penetrate the restricted areas of the M2 channel.<ref name="Stouffer" />


==Additional Resources==
==Additional Resources==