2hu6: Difference between revisions
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[[Image:2hu6.png|left|200px]] | [[Image:2hu6.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[2hu6]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HU6 OCA]. | |||
==See Also== | |||
*[[Elastase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Papakyriakou, A.]] | [[Category: Papakyriakou, A.]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Hydrolase]] | |||
[[Category: Hydroxamic acid]] | [[Category: Hydroxamic acid]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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[[Category: Matrix metalloproteinase]] | [[Category: Matrix metalloproteinase]] | ||
[[Category: Mmp-12]] | [[Category: Mmp-12]] | ||
Revision as of 08:40, 26 December 2010
Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor
Template:ABSTRACT PUBMED 16899369
About this Structure
2hu6 is a 1 chain structure of Elastase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mannino C, Nievo M, Machetti F, Papakyriakou A, Calderone V, Fragai M, Guarna A. Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. Bioorg Med Chem. 2006 Nov 15;14(22):7392-403. Epub 2006 Aug 8. PMID:16899369 doi:10.1016/j.bmc.2006.07.028
