2c2s: Difference between revisions
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[[Image:2c2s.png|left|200px]] | [[Image:2c2s.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[2c2s]] is a 2 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2S OCA]. | |||
==See Also== | |||
*[[Dihydrofolate reductase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Nonclassical antifolate]] | [[Category: Nonclassical antifolate]] | ||
[[Category: One-carbon metabolism]] | [[Category: One- carbon metabolism]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Reductase]] | [[Category: Reductase]] | ||
Revision as of 08:47, 26 December 2010
HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 2,4-DIAMINO-5-(1-O-CARBORANYLMETHYL)-6-METHYLPYRIMIDINE, A NOVEL BORON CONTAINING, NONCLASSICAL ANTIFOLATE
Template:ABSTRACT PUBMED 17569517
About this Structure
2c2s is a 2 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Reynolds RC, Campbell SR, Fairchild RG, Kisliuk RL, Micca PL, Queener SF, Riordan JM, Sedwick WD, Waud WR, Leung AK, Dixon RW, Suling WJ, Borhani DW. Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation. J Med Chem. 2007 Jul 12;50(14):3283-9. Epub 2007 Jun 15. PMID:17569517 doi:10.1021/jm0701977
