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Revision as of 09:01, 26 December 2010

File:1nt1.png

Template:STRUCTURE 1nt1

thrombin in complex with selective macrocyclic inhibitor

Template:ABSTRACT PUBMED 12873514

About this Structure

1nt1 is a 2 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Nantermet PG, Barrow JC, Newton CL, Pellicore JM, Young M, Lewis SD, Lucas BJ, Krueger JA, McMasters DR, Yan Y, Kuo LC, Vacca JP, Selnick HG. Design and synthesis of potent and selective macrocyclic thrombin inhibitors. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2781-4. PMID:12873514

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