2pob: Difference between revisions

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Revision as of 09:17, 26 December 2010

File:2pob.png

Template:STRUCTURE 2pob

PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709

Template:ABSTRACT PUBMED 17533125

About this Structure

2pob is a 2 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Trump RP, Cobb JE, Shearer BG, Lambert MH, Nolte RT, Willson TM, Buckholz RG, Zhao SM, Leesnitzer LM, Iannone MA, Pearce KH, Billin AN, Hoekstra WJ. Co-crystal structure guided array synthesis of PPARgamma inverse agonists. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3916-20. Epub 2007 May 18. PMID:17533125 doi:10.1016/j.bmcl.2007.04.111

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