2bre: Difference between revisions

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Revision as of 19:50, 26 December 2010

File:2bre.png

Template:STRUCTURE 2bre

STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90.

Template:ABSTRACT PUBMED 15955698

About this Structure

2bre is a 2 chain structure of Heat Shock Proteins with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cheung KM, Matthews TP, James K, Rowlands MG, Boxall KJ, Sharp SY, Maloney A, Roe SM, Prodromou C, Pearl LH, Aherne GW, McDonald E, Workman P. The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3338-43. PMID:15955698 doi:10.1016/j.bmcl.2005.05.046

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