3c1k: Difference between revisions
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[[Image:3c1k.png|left|200px]] | [[Image:3c1k.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[3c1k]] is a 2 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C1K OCA]. | |||
==See Also== | |||
*[[Hirudin]] | |||
==Reference== | ==Reference== | ||
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[[Category: Thrombin inhibitor complex]] | [[Category: Thrombin inhibitor complex]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 21:02, 26 December 2010
Crystal structure of thrombin in complex with inhibitor 15
Template:ABSTRACT PUBMED 18291642
About this Structure
3c1k is a 2 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, McMasters DR, Krueger JA, Lewis SD, Lucas BJ, Kuo LC, Yan Y, Lynch JJ, Lyle EA. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2062-6. Epub 2008 Jan 30. PMID:18291642 doi:10.1016/j.bmcl.2008.01.098
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Categories:
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- Homo sapiens
- Thrombin
- Yan, Y.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Pharmaceutical
- Polymorphism
- Protease
- Protease inhibitor
- Secreted
- Serine protease
- Serine protease inhibitor
- Sulfation
- Thrombin inhibitor complex
- Zymogen