1u70: Difference between revisions
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[[Image:1u70.png|left|200px]] | [[Image:1u70.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[1u70]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U70 OCA]. | |||
==See Also== | |||
*[[Dihydrofolate reductase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Cody, V.]] | [[Category: Cody, V.]] | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Oxidoreductase]] | |||
[[Category: Variant dhfr mouse]] | [[Category: Variant dhfr mouse]] | ||
Revision as of 21:23, 26 December 2010
Understanding the Role of Leu22 Variants in Methotrexate Resistance: Comparison of Wild-type and Leu22Arg Variant Mouse and Human Dihydrofolate Reductase
Template:ABSTRACT PUBMED 15681865
About this Structure
1u70 is a 1 chain structure of Dihydrofolate reductase with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Cody V, Luft JR, Pangborn W. Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH. Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):147-55. Epub 2005, Jan 19. PMID:15681865 doi:https://dx.doi.org/10.1107/S0907444904030422