3fl9: Difference between revisions

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Revision as of 00:07, 27 December 2010

File:3fl9.png

Template:STRUCTURE 3fl9

Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with trimethoprim

Template:ABSTRACT PUBMED 19364848

About this Structure

3fl9 is a 8 chain structure of Dihydrofolate reductase with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul;53(7):3065-73. Epub 2009 Apr 13. PMID:19364848 doi:10.1128/AAC.01666-08

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