1j3k: Difference between revisions
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Revision as of 01:00, 27 December 2010
Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP
Template:ABSTRACT PUBMED 12704428
About this Structure
1j3k is a 4 chain structure of Dihydrofolate reductase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
See Also
Reference
- Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921
