3is9: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3is9]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_bh10 Human immunodeficiency virus type 1 bh10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IS9 OCA]. | |||
==See Also== | |||
*[[Reverse transcriptase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Zinc]] | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 01:08, 27 December 2010
Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).
Template:ABSTRACT PUBMED 19775161
About this Structure
3is9 is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.
See Also
Reference
- Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J Med Chem. 2009 Oct 22;52(20):6467-73. PMID:19775161 doi:10.1021/jm901167t
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Human immunodeficiency virus type 1 bh10
- Arnold, E.
- Bauman, J D.
- Das, K.
- Ho, W C.
- Adam
- Aid
- Aspartyl protease
- Cell membrane
- Cytoplasm
- Dna integration
- Dna recombination
- Dna-directed dna polymerase
- Endonuclease
- Hiv
- Hydrolase
- Lipoprotein
- Membrane
- Metal-binding
- Multifunctional enzyme
- Myristate
- Nnrti
- Nonnucleoside inhibitor
- Nuclease
- Nucleotidyltransferase
- Nucleus
- P51/p66
- Phosphoprotein
- Protease
- Rna-binding
- Rna-directed dna polymerase
- Transferase
- Transferase-hydrolase complex
- Viral nucleoprotein
- Virion
- Zinc
- Zinc-finger
