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Revision as of 02:16, 27 December 2010

File:1qbv.png

Template:STRUCTURE 1qbv

CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR

Template:ABSTRACT PUBMED 9622548

About this Structure

1qbv is a 3 chain structure of Hirudin with sequence from Hirudinaria manillensis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bone R, Lu T, Illig CR, Soll RM, Spurlino JC. Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes. J Med Chem. 1998 Jun 4;41(12):2068-75. PMID:9622548 doi:10.1021/jm970796l

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