1sc7: Difference between revisions

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{{Seed}}
[[Image:1sc7.png|left|200px]]
[[Image:1sc7.png|left|200px]]


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{{ABSTRACT_PUBMED_15801827}}
{{ABSTRACT_PUBMED_15801827}}


==Disease==
==About this Structure==
Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126420 126420]]
[[1sc7]] is a 4 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC7 OCA].


==About this Structure==
==See Also==
1SC7 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC7 OCA].
*[[Topoisomerase]]


==Reference==
==Reference==
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[[Category: Poison]]
[[Category: Poison]]
[[Category: Topoisomerase i]]
[[Category: Topoisomerase i]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:30:28 2009''

Revision as of 02:35, 27 December 2010

File:1sc7.png

Template:STRUCTURE 1sc7

Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex

Template:ABSTRACT PUBMED 15801827

About this Structure

1sc7 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p

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