2p8s: Difference between revisions
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Revision as of 11:50, 3 January 2011
Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor
Template:ABSTRACT PUBMED 17433672
About this Structure
2p8s is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE. Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3384-7. Epub 2007 Apr 2. PMID:17433672 doi:10.1016/j.bmcl.2007.03.095