2rgu: Difference between revisions
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[[Image:2rgu.png|left|200px]] | [[Image:2rgu.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[2rgu]] is a 2 chain structure of [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGU OCA]. | |||
==See Also== | |||
*[[Dipeptidyl peptidase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
Revision as of 11:56, 3 January 2011
Crystal structure of complex of human DPP4 and inhibitor
Template:ABSTRACT PUBMED 18052023
About this Structure
2rgu is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin -2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. J Med Chem. 2007 Dec 27;50(26):6450-3. Epub 2007 Dec 1. PMID:18052023 doi:10.1021/jm701280z
