3ot3: Difference between revisions

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Revision as of 15:34, 5 January 2011

File:3ot3.png

Template:STRUCTURE 3ot3

X-ray crystal structure of compound 22k bound to human Chk1 kinase domain

Template:ABSTRACT PUBMED 21094607

About this Structure

3ot3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Labroli M, Paruch K, Dwyer MP, Alvarez C, Keertikar K, Poker C, Rossman R, Duca JS, Fischmann TO, Madison V, Parry D, Davis N, Seghezzi W, Wiswell D, Guzi TJ. Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach-Part 2. Bioorg Med Chem Lett. 2010 Oct 28. PMID:21094607 doi:10.1016/j.bmcl.2010.10.114

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