3nlu: Difference between revisions

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Revision as of 06:23, 19 January 2011

File:3nlu.jpg

Template:STRUCTURE 3nlu

Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlu is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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