Colicin M: Difference between revisions
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Colicin M is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them by inhibiting synthesis of peptidoglycan, preventing synthesis of the cell wall and ultimately leading to cell | Colicin M is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them by inhibiting synthesis of peptidoglycan - murein, preventing synthesis of the cell wall and ultimately leading to cell lysis. | ||
==Synthesis and release== | ==Synthesis and release== | ||
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==Killing Activities== | ==Killing Activities== | ||
ColM shows enzymatic properties of degradation of lipid I and lipid II peptidoglycan intermediates. The cleavage occurs between the lipid moiety and the pyrophosphoryl groups. This then leads to the arrest of peptidoglycan polymerisation<ref> PMID: 16777846 </ref>, rather than the direct degradation of the peptidoglycan<ref> PMID: 7012126 </ref>. | |||
==References== | |||
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