Peroxiredoxin: Difference between revisions

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{{STRUCTURE_1qq2|  PDB=1qq2  | SIZE=300| SCENE=Peroxiredoxin/Cv/1 |right|CAPTION=Peroxiredoxin [[1qq2]]}}
{{STRUCTURE_1qq2|  PDB=1qq2  | SIZE=300| SCENE=Peroxiredoxin/Cv/1 |right|CAPTION=Peroxiredoxin [[1qq2]]}}


[[Peroxiredoxin]] (Prx) is an antioxidant enzyme.  In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide.  The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. The images at the left and at the right correspond to one representative Prx, ''i.e.'' the crystal structure of Peroxiredoxin from rat ([[1qq2]]).
[[Peroxiredoxin]] (Prx) is an antioxidant enzyme.  In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide.  The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. Prx 5 is expressed in mammalian tissue. The images at the left and at the right correspond to one representative Prx, ''i.e.'' the crystal structure of Peroxiredoxin from rat ([[1qq2]]).


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[[1qq2]] – 2Cys-Prx – rat<br />
[[1qq2]] – 2Cys-Prx – rat<br />
[[2c0d]] – 2Cys-Prx – ''Plasmodium falciparum''<br />
[[2c0d]] – Pf2Cys-Prx – ''Plasmodium falciparum''<br />
[[1xiy]] – Pf1Cys-Prx<br />
[[1xcc]], [[2h01]] - 1Cys-Prx – ''Plasmodium yoelii''<br />
[[2i81]] - 2Cys-Prx – ''Plasmodium vivax''<br />
[[1qmv]] - h2Cys-Prx – human<br />
[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br />
[[2z9s]] – Prx 1 (mutant) - rat<br />
[[2pn8]] – hPrx 4<br />
[[1urm]] – hPrx 5 (mutant) – human<br />
[[1urm]] – hPrx 5 (mutant) – human<br />
[[2vl2]], [[2vl3]], [[2vl9]] – hPrx 5<br />
[[2vl2]], [[2vl3]], [[2vl9]], [[1h4o]], [[1hd2]], [[1oc3]]  – hPrx 5<br />
[[3mng]] – hPrx 5+DTT<br />
[[3mng]] – hPrx 5+DTT<br />
[[2av5]] – Prx dot5 C-termianl (mutant) -yeast<br />
[[2wfc]] – lPrx 5 - lugworm<br />
[[2v2g]] – lPrx 6 <br />
[[2v32]], [[2v41]] – lPrx 6 (mutant)<br />
[[2a4v]] – yPrx dot5 C-termianl (mutant) – yeast<br />
[[3cmi]] – yPrx hyr1<br />
[[1tp9]] – Prx  II – ''Populus trichocarpa''<br />
[[2pwj]] – Prx II – garden pea<br />
[[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br />
[[1we0]] – Prx – ''Amphibacillus xylanus''<br />
[[1zye]] – Prx III (mutant) – bovine<br />
[[2cv4]], [[2cx3]], [[2cx4]] – Prx – ''Aeropyrum pernix''<br />
[[3drn]] – SsPrx – ''Sulfolobus solfataricus''<br />
[[3hjp]] – SsPrx (mutant)<br />
[[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br />
 


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[[Category:Topic Page]]