TolQ: Difference between revisions
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==Structure== | ==Structure== | ||
There are three membrane spanning segments in TolQ. TM1 is connected to TM2 via a large cytoplasmic loop, with the N-terminal ending in the periplasm. | There are three membrane spanning segments in TolQ. TM1 is connected to TM2 via a large cytoplasmic loop, with the N-terminal ending in the periplasm. | ||
[[Image:TolQ.jpg|600px|right|thumb| The TolQ Membrane-spanning domains]] | |||
It has been shown that 4 to 6 TolQ molecules associate in the TolQRA complex, and that they form multimers which interact with the transmembrane helices (TMH) of TolQ, TolR and TolA <ref>PMID: 21285349</ref>. The multimers are formed by the three TMHs <ref>PMID: 8300535</ref> of TolQ, the last of which undergo a conformational change to form a hairpin, while the first TMH forms an intermolecular interaction | It has been shown that 4 to 6 TolQ molecules associate in the TolQRA complex, and that they form multimers which interact with the transmembrane helices (TMH) of TolQ, TolR and TolA <ref>PMID: 21285349</ref>. The multimers are formed by the three TMHs <ref>PMID: 8300535</ref> of TolQ, the last of which undergo a conformational change to form a hairpin, while the first TMH forms an intermolecular interaction | ||
