TonB: Difference between revisions
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TonB is involved in the uptake of iron as a component of the TonB/ExbB/ExbD complex of the [[Ton]] system. | TonB is involved in the uptake of iron as a component of the TonB/[[ExbB]]/[[ExbD]] complex of the [[Ton]] system. | ||
==Structure== | ==Structure== | ||
TonB and ExbD bind to ExbB in a protein complex that prevents the degradation of the TonB protein. TonB and ExbD are anchored to the cytoplasmic membrane via their N-terminal hydrophobic sequences, with the rest of the protein complex extending into the periplasmic space, allowing for interaction with outer membrane proteins.<ref name='Kampfenkel'>PMID: 8449962</ref> | |||
==Function== | ==Function== | ||
The activity of TonB is determined by the presence of ExbB and ExbD. <ref name='Kampfenkel'>PMID: 8449962</ref> | |||
==Regulation== | ==Regulation== | ||
Revision as of 11:08, 14 February 2011
TonB is involved in the uptake of iron as a component of the TonB/ExbB/ExbD complex of the Ton system.
Structure
TonB and ExbD bind to ExbB in a protein complex that prevents the degradation of the TonB protein. TonB and ExbD are anchored to the cytoplasmic membrane via their N-terminal hydrophobic sequences, with the rest of the protein complex extending into the periplasmic space, allowing for interaction with outer membrane proteins.[1]
Function
The activity of TonB is determined by the presence of ExbB and ExbD. [1]
