Colicin A: Difference between revisions
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Colicin A binds to the BtuB Vitamin B12 outer membrane receptor of the target cell, and uses the [[Tol]] system to translocate across the membrane, specifically TolQRAB, alongside the OmpF protein. Its use of the Tol system means that Colicin A is in the A group of colicins. | Colicin A binds to the BtuB Vitamin B12 outer membrane receptor of the target cell, and uses the [[Tol]] system to translocate across the membrane, specifically TolQRAB, alongside the OmpF protein. Its use of the Tol system means that Colicin A is in the A group of colicins. | ||
This structure shows the <scene name='Colicin_A/Tolbbox/1'>TolB box</scene>of colA bound to TolB. | This structure shows the <scene name='Colicin_A/Tolbbox/1'>TolB box</scene> of colA bound to <scene name='Colicin_A/Tolb/1'>TolB</scene>. | ||
==Cytotoxic activity== | ==Cytotoxic activity== | ||