Atropine: Difference between revisions

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==== '''Atropine in the Active Site of Phospholipase 2A''' ====
==== '''Atropine in the Active Site of Phospholipase 2A''' ====


Atropine is an inhibitor of phospholipase 2A, and can be seen in complex with this enzyme on the left. The <scene name='Sandbox_53/Atropine_structure/1'>structure of atropine</scene> can be seen more clearly in gray using the ball-and stick representation of the drug and protein. It can also be seen in green in this (space-filling model). Finally, the (N and C terminal) portions of the protein can be highlighted, and the active site with atropine can be seen in the middle of the protein.  
Atropine is an inhibitor of phospholipase 2A, and can be seen in complex with this enzyme on the left. The <scene name='Sandbox_53/Atropine_structure/1'>structure of atropine</scene> can be seen more clearly in gray using the ball-and stick representation of the drug and protein. It can also be seen in green in this <scene name='Sandbox_53/Phospholipase2a_composition/1'>space-filling model</scene>, where protein appears in brown, ligands appear in green, and solvents appear in blue. Finally, the  
<scene name='Sandbox_53/Phospholipase2a_rainbow/1'>N to C terminal</scene> portions of the protein can be highlighted from blue to red in a rainbow, and the active site with atropine can be seen in the middle of the protein.  


Atropine interacts with phospholipase 2A at residues asp29 and tyr49 on the protein. The  
Atropine interacts with phospholipase 2A at residues asp29 and tyr49 on the protein. The