2hl4: Difference between revisions

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Revision as of 18:34, 14 March 2011

File:2hl4.png

Template:STRUCTURE 2hl4

Crystal structure analysis of human carbonic anhydrase II in complex with a benzenesulfonamide derivative

Template:ABSTRACT PUBMED 17251017

About this Structure

2hl4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Di Fiore A, Scozzafava A, Winum JY, Montero JL, Pedone C, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1726-31. Epub 2007 Jan 8. PMID:17251017 doi:10.1016/j.bmcl.2006.12.099
  2. Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:https://dx.doi.org/10.1002/prot.340040406

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