2v22: Difference between revisions
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Revision as of 21:18, 14 March 2011
REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS
Template:ABSTRACT PUBMED 17051658
About this Structure
2v22 is a 4 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Andrews MJ, Kontopidis G, McInnes C, Plater A, Innes L, Cowan A, Jewsbury P, Fischer PM. REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors. Chembiochem. 2006 Dec;7(12):1909-15. PMID:17051658 doi:10.1002/cbic.200600189
- Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:https://dx.doi.org/10.1016/j.chembiol.2005.11.011
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Andrews, M J.
- Cowan, A.
- Fischer, P M.
- Innes, L.
- Jewsbury, P.
- Kontopidis, G.
- Mcinnes, C.
- Plater, A.
- Active
- Atp-binding
- Cdk2
- Cell cycle
- Cell division
- Cyclin
- Cyclin groove
- Inhibition
- Kinase
- Mitosis
- Nonpeptide
- Nucleotide-binding
- Phosphorylation
- Polymorphism
- Serine/threonine-protein kinase
- Transferase
