3d20: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3d20]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D20 OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Zinc]] | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 22:09, 14 March 2011
Crystal structure of HIV-1 mutant I54V and inhibitor DARUNAVIA
Template:ABSTRACT PUBMED 18597780
About this Structure
3d20 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT. Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J Mol Biol. 2008 Aug 1;381(1):102-15. Epub 2008 Jul 1. PMID:18597780 doi:10.1016/j.jmb.2008.05.062
- Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007
- Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- HIV-1 retropepsin
- Human immunodeficiency virus 1
- Ghosh, A K.
- Harrison, R W.
- Kovalesky, A Y.
- Liu, F.
- Tie, Y.
- Weber, I T.
- Aid
- Aspartyl protease
- Capsid maturation
- Capsid protein
- Cytoplasm
- Dna integration
- Dna recombination
- Dna-directed dna polymerase
- Drug resistance
- Endonuclease
- Flap mutant
- Hiv-1
- Hydrolase
- I54v
- Lipoprotein
- Magnesium
- Membrane
- Metal-binding
- Multifunctional enzyme
- Myristate
- Nuclease
- Nucleotidyltransferase
- Nucleus
- Phosphoprotein
- Protease
- Ribosomal frameshifting
- Rna-binding
- Rna-directed dna polymerase
- Transferase
- Viral nucleoprotein
- Virion
- Zinc
- Zinc-finger
