3bva: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3bva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVA OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Mutation]] | [[Category: Mutation]] | ||
Revision as of 22:14, 14 March 2011
Cystal structure of HIV-1 Active Site Mutant D25N and p2-NC analog inhibitor
Template:ABSTRACT PUBMED 18281688
About this Structure
3bva is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Sayer JM, Liu F, Ishima R, Weber IT, Louis JM. Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease. J Biol Chem. 2008 May 9;283(19):13459-70. Epub 2008 Feb 15. PMID:18281688 doi:10.1074/jbc.M708506200
- Ishima R, Torchia DA, Lynch SM, Gronenborn AM, Louis JM. Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor. J Biol Chem. 2003 Oct 31;278(44):43311-9. Epub 2003 Aug 21. PMID:12933791 doi:https://dx.doi.org/10.1074/jbc.M307549200
- Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095
