1t8a: Difference between revisions
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[[Image:1t8a.png|left|200px]] | [[Image:1t8a.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[1t8a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8A OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Matthews, B W.]] | [[Category: Matthews, B W.]] | ||
[[Category: Yousef, M S.]] | [[Category: Yousef, M S.]] | ||
[[Category: Hydrolase]] | |||
[[Category: Molecular switch]] | [[Category: Molecular switch]] | ||
[[Category: Nano-bitechnology]] | [[Category: Nano-bitechnology]] | ||
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[[Category: Protein engineering]] | [[Category: Protein engineering]] | ||
[[Category: T4 lysozyme]] | [[Category: T4 lysozyme]] | ||
Revision as of 22:24, 14 March 2011
USE OF SEQUENCE DUPLICATION TO ENGINEER A LIGAND-TRIGGERED LONG-DISTANCE MOLECULAR SWITCH IN T4 LYSOSYME
Template:ABSTRACT PUBMED 15286283
About this Structure
1t8a is a 1 chain structure with sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA.
Reference
- Yousef MS, Baase WA, Matthews BW. Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11583-6. Epub 2004 Jul 30. PMID:15286283 doi:10.1073/pnas.0404482101
- Sagermann M, Baase WA, Matthews BW. Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6078-83. PMID:10339544
- Sagermann M, Gay L, Matthews BW. Long-distance conformational changes in a protein engineered by modulated sequence duplication. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9191-5. Epub 2003 Jul 17. PMID:12869697 doi:10.1073/pnas.1633549100
