3juh: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3juh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ymi 1ymi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUH OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Wnt signaling pathway]] | [[Category: Wnt signaling pathway]] | ||
Revision as of 22:31, 14 March 2011
Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity
Template:ABSTRACT PUBMED 18291315
About this Structure
3juh is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entries and 1ymi. Full crystallographic information is available from OCA.
Reference
- Raaf J, Brunstein E, Issinger OG, Niefind K. The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules. Chem Biol. 2008 Feb;15(2):111-7. PMID:18291315 doi:https://dx.doi.org/10.1016/j.chembiol.2007.12.012
- Yde CW, Ermakova I, Issinger OG, Niefind K. Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate. J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18. PMID:15740749 doi:https://dx.doi.org/10.1016/j.jmb.2005.01.003
- PMID: https://pubmed.ncbi.nlm.nih.gov/19693436/